Neocide 3
Bacterial disease in koi is a serious
concern for both the hobbyist and the
professional koi keeper. Untreated,
bacterial disease often results in fin rot,
ulceration (Hole Disease) and mortality.
Until now, the most effective treatment
has been the administration of antibiotics
by means of injection. Obtaining the
appropriate injectable antibiotics is often
difficult for the average hobbyist, as
these drugs and supplies require a

prescription from a licensed veterinarian. Additionally, many hobbyists are
understandably reluctant to inject their koi, having had no training or experience in this
procedure.
Neocide 3 is administered by dipping the koi in solution, rather than be injection.
Neocide 3 is a user-friendly treatment that can be easily administered by both novice and
professional koi keepers.
Neocide 3 provides an excellent and often more effective and environmentally friendly
alternative to dealing with a wide range of bacterial issues in koi.
What is Neocide 3 and how does it work?
Neocide 3 is a concentrate of NeoMycin with an antibiotic potentiator, developed by the
University of Georgia College of Veterinary Medicine.
Neocide 3 has been found to be beneficial in treating superficial infections in animals
maintained in both experimental and field conditions. Among the advantages of Neocide
are its ease of use, safety, and applicability with a wide-variety of antibiotics and
effectiveness against gram-positive and gram-negative bacterial pathogens.
Neocide 3 has a rather interesting mode of activity that facilitates its spectrum of activity.
Neocide creates holes in the bacterial cell wall which in-turn allows antibiotics to flood the
organism, destroys the effectiveness of the bacteria's efflux pump and facilitates osmotic
collapse of the bacterium. Because the potentiator causes direct physical damage to the
bacteria, one is able to:
Kill otherwise drug-resistant bacteria with low class antibiotics
Use less antibiotic than would normally be necessary
Stimulate wound healing
Reduce the likelihood that exposed bacteria will develop resistance to the chosen
antibiotic
Neocide 3 is available in dry crystalline form, in both 1 and 5 gallon doses.
Dr. Greco's Koi and Supplies P.O. Box Mount Sinai, N.Y. 11766 1-800-xxx-xxxx Koi viewed by Appointment only
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